Research and Testimonials
behind the Theory

As with most things, Carbon60 in oil for human consumption and health, was merely a theory.  Research concluded and proved that this theory is now a reality.  The “Baati/Paris” study is the very foundation as to how we make our KARABUN products. 

Lab-work-Karabun

Abstract

The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene

Referred to by:

Tarek Baati
Fanchon Bourasset
Najla Gharbi
Leila Njim
Manef Abderrabba
Abdelhamid Kerkeni
Henri Szwarc
Fathi Moussa

THE BAATI/PARIS STUDY IS AVAILBLE HERE
Countless studies showed that [60]fullerene (C60) and derivatives could have many potential biomedical applications. However, while several independent research groups showed that C60 has no acute or sub-acute toxicity in various experimental models, more than 25 years after its discovery the in vivo fate and the chronic effects of this fullerene remain unknown. If the potential of C60 and derivatives in the biomedical field have to be fulfilled these issues must be addressed. Here we show that oral administration of C60 dissolved in olive oil (0.8 mg/ml) at reiterated doses (1.7 mg/kg of body weight) to rats not only does not entail chronic toxicity but it almost doubles their lifespan. The effects of C60-olive oil solutions in an experimental model of CCl4 intoxication in rat strongly suggest that the effect on lifespan is mainly due to the attenuation of age-associated increases in oxidative stress. Pharmacokinetic studies show that dissolved C60 is absorbed by the gastro-intestinal tract and eliminated in a few tens of hours. These results of importance in the fields of medicine and toxicology should open the way for the many possible -and waited for- biomedical applications of C60 including cancer therapy, neurodegenerative disorders, and ageing.

In 2012, researches in Argentina have shown, using computer simulations, that C60 is able to destabilize the structure of the amyloid-β protein and prevent the formation of the amyloid plaques. The hope is for C60 to slow or reverse Alzheimer’s disease which is estimated to affect 35 million people world wide.

Lab Test

The highest standard product is our promise:

  • Each product is HPLC tested so that KARABUN C60 delivers your best option in achieving a healthier and fuller life
  • Optimal saturation of olive oil with no test result discrepancies and guaranteed highest saturation on the market – above 0.8gr/1L

(The sample test link is below)

 

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Abstract 2

Amyloid-β fibril disruption by C60-molecular guidance for rational drug design.

Referred to by:

Andujar SA
Lugli F
Höfinger S
Enriz RD
Zerbetto F.

More information can be found here
The WHO has listed Alzheimer’s disease among the major neurological disorders with an estimated 35 million people affected worldwide. Amyloid-β is mostly believed to be the causative factor in Alzheimer’s disease and the severity of the disease correlates with the tendency of amyloid-β to form aggregation patterns-plaques. Lacking effective medication, the identification of any underlying mechanistic principles regarding plaque formation appears to be crucial. Here we carry out computer simulations to study the effect of C60 on structure and stability of an idealised pentameric construct of amyloid-β units (a model fibril). A binding site on top of the structurally ordered stack of β-sheets is identified that triggers structural alterations at the turn region of the hook-like β-sheet assembly. Significant structural alterations are: (i) the destruction of regular helical twist, (ii) the loss of a stabilizing salt bridge and (iii) the loss of a stabilizing hydrophobic interaction close to the turn. Consequently, the main effect of C60 is the induction of sizable destabilization in native fibril structure. These structural insights may serve as a molecular guide for further rational drug design of effective inhibitors targeting fibril formation in Alzheimer’s disease.

ONGOING RESEARCH

Backed by continued studies, C60’s results show significant improvement in our health and lives.  No matter what your current lifestyle entails, KARABUN will help you improve your quality of life and stay healthier for longer. The studies and testimonials can be shown to benefit people with:

  • Reduced pain and swelling in rheumatoid arthritis
  • Recovery and regrowth of healthy skin in psoriasis patients
  • Reduced inflammation and itching in eczema
  • Increased stamina
  • Increased recovery and vitality after exercise
  • Assist with weight loss and improves Metabolic Syndrome
  • Radiant complexion and longevity
  • Optimal hair growth and regrowth
  • Protection again cancer
  • Reduced risk of Alzheimer’s disease
  • Quality sleep

There is no better time than now.  Give your body the chance to building immunity, stay healthy and strong, fight those free radicals that we expose our bodies to everyday.  KARABUN C60 is here to optimise that “one body” that we have!  Do not wait for any unwanted negative health effects – KARABUN is the supplement of choice.